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Panexin

No more serum testing! Panexin products are fully defined serum replacements developed by PAN-Biotech. They can be used for the cultivation of adherent and non-adherent cells under serum-free or serum-reduced conditions. For more demanding cell lines we also designed Panexin NTA (adherent cells) and NTS (suspension cells).
Enjoy the reproducibility and the flexibility!



Applications
  • As serum replacement or medium supplement to increase the productivity in industrial cell cultures (CHO, MDCK, Vero, Hybridoma etc.)
  • To avoid the exosoms or stimulatory effects of growth factors in serum
  • To prevent the overgrowth of the culture by fibroblasts in coculture or in highly differentiated epithelial primary cultures
  • To guarantee the reproducibility and sensitivity in cell-based in vitro assays
  • To generally reduce the amount of serum due to ethical concerns, lot-to-lot variability or high costs
Advantages
  • No more serum testing
  • High reproducibility
  • Flexibility
  • Reliability
  • Cost efficiency
  • Lower investment
  • Simplified downstream
  • GMP compliant
➔ References
Do you know?

Serum introduces several severe unknown variables into the cell culture procedure, as serum (a) is a poorly defined supplement (Bjare, 1992; Gstraunthaler, 2003); (b) batches show typically qualitative variations and different amount of endotoxins, haemoglobin and other factors (Price and Gregory, 1982); (c) can be a potential source of contamination (Dormont, 1999; Eliot, 1999; Wessman and Levings, 1999) and (d) does not represent physiological conditions. Therefore, FBS may alter the experimental output or the performance of assays.

Media with 10% FBS:
  • FBS contains hundreds of distinct proteins and thousands of metabolites in undefined, varying concentrations
  • Resulting in inconsistent results and unreproducible data
  • Data in figure from M. Baker, Nature 537 2016 433–435
Media with 1% FBS and 9% Panexin:
  • The variation of bioactive components in FBS from lot to lot can be reduced tremendously
  • Can be easily adaped to a wide range of cell types
  • With significantly improved reproducibility
  • More independent from the lot, the origin and the supplier of FBS
Serum-free media with Panexin:
  • Constant quality
  • Highest reproducibility
  • No more serum testing!
ProductDescriptionXFFD
Panexin basic Suitable for a broad range of cells, to replace, or to reduce FBS x
Panexin NTA Optimized for adherent cells x
Panexin NTS Optimized for non-adherent cells x
Panexin pharma grade Components with animal origin are replaced by synthetic or recombinant products, for example BSA is replaced by HSA x

XF: Xeno free, free of components with animal origin
FD: Fully defined, purity of any components > 98%

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Kontakt

Geschäftszeiten:
Mo-Fr: 8:00 - 17:00 Uhr (MEZ)

E-Mail: shop@pan-biotech.de
Tel: +49 (0) 8543 60 16 - 30
Fax: +49 (0) 8543 60 16 - 49

Versandinformation

Der Versand unserer Produkte erfolgt Montag bis Donnerstag. Um die Qualität unserer gefrorenen Produkte zu gewährleisten, erfolgt donnerstags kein Versand.
Weitere Information finden Sie in unseren Geschäftsbedingungen und unter Versand!